Journal of Pharmacology and Experimental Therapeutics

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  Año 2005, Vol. 315, Número 2

  • In Silico Predictions of Blood-Brain Barrier Penetration: Considerations to "Keep in Mind"

    J. T. Goodwin

    págs. 477-483

    

  • Interaction with Blood Components Plays a Crucial Role in Asialoglycoprotein Receptor-Mediated in Vivo Gene Transfer by Galactosylated Lipoplex

    S. Fumoto, S. Kawakami

    págs. 484-493

    

  • The Effect of Dipyridamole on Vascular Cell-Derived Reactive Oxygen Species

    S. Chakrabarti

    págs. 494-500

    

  • A New ATP-Sensitive Potassium Channel Opener Protects the Kidney from Hypertensive Damage in Spontaneously Hypertensive Rats

    Y.-L. Zhang, H. Xue

    págs. 501-509

    

  • In Vitro Evaluation of the Angiostatic Potential of Drugs Using an Endothelialized Tissue-Engineered Connective Tissue

    P.-L. Tremblay

    págs. 510-516

    

  • Impairment of Hyperpolarization-Activated, Cyclic Nucleotide-Gated Channel Function by the Intravenous General Anesthetic Propofol

    L. P. Cacheaux

    págs. 517-525

    

  • Human U251 Glioma Cell Proliferation Is Suppressed by HET0016 [N-Hydroxy-N'-(4-butyl-2-methylphenyl)formamidine], a Selective Inhibitor of CYP4A

    R. J. Roman, P. A. Edwards, M. Guo, J. R. Falck

    págs. 526-533

    

  • Functional Characterization of Rat Organic Anion Transporter 5 (Slc22a19) at the Apical Membrane of Renal Proximal Tubules

    H. Nonoguchi, H. Yokoyama, N. Anzai, P. Jutabha, A. Enomoto

    págs. 534-544

    

  • Human Expanded Polyglutamine Androgen Receptor Mutants in Neurodegeneration as a Novel Ligand Target

    T. Furutani, K.-i. Takeyama

    págs. 545-552

    

  • Anti-Inflammatory Effects of Inhibiting the Amine Oxidase Activity of Semicarbazide-Sensitive Amine Oxidase

    L. M. Salter-Cid

    págs. 553-562

    

  • Differential Regulation of Cystic Fibrosis Transmembrane Conductance Regulator by Interferon gamma in Mast Cells and Epithelial Cells

    R. Dery, D. Nahirney, M. Kulka

    págs. 563-570

    

  • Synthetic Pyrrole-Imidazole Polyamide Inhibits Expression of the Human Transforming Growth Factor-beta1 Gene

    N. Fukuda, Y.-M. Lai

    págs. 571-575

    

  • Signal Transduction for Proteinase-Activated Receptor-2-Triggered Prostaglandin E~2 Formation in Human Lung Epithelial Cells

    N. Kawao, M. Nagataki, K. Nagasawa

    págs. 576-589

    

  • The Metabotropic Glutamate 5 Receptor Antagonist 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine Reduces Ethanol Self-Administration in Multiple Strains of Alcohol-Preferring Rats and Regulates Olfactory Glutamatergic Systems

    M. S. Cowen

    págs. 590-600

    

  • DPI-221 [4-((alpha-S)-alpha-((2S,5R)-2,5-Dimethyl-4-(3-fluorobenzyl)-1-piperazinyl)benzyl)-N,N-diethylbenzamide]: A Novel Nonpeptide delta Receptor Agonist Producing Increased Micturition Interval in Normal Rats

    J. D. S. Holt, M. J. Watson

    págs. 601-608

    

  • Nociceptive Effect of Subcutaneously Injected Interleukin-12 Is Mediated by Endothelin (ET) Acting on ET~B Receptors in Rats

    I. R. S. Schivo, R. O. Molina, W. A. Verri

    págs. 609-615

    

  • MEN16132, a Novel Potent and Selective Nonpeptide Kinin B~2 Receptor Antagonist: In Vivo Activity on Bradykinin-Induced Bronchoconstriction and Nasal Mucosa Microvascular Leakage in Anesthetized Guinea Pigs

    Claudio Valenti, S. Giuliani, C. Cialdai

    págs. 616-623

    

  • Prevention of the Ultraviolet B-Mediated Skin Photoaging by a Nuclear Factor kappaB Inhibitor, Parthenolide

    K. Asamitsu, K. Tanaka, J. Hasegawa

    págs. 624-630

    

  • Assessment of the Influence of Histaminergic Actions on Cocaine-Like Effects of 3alpha-Diphenylmethoxytropane Analogs

    T. A. Kopajtic, V. C. Campbell

    págs. 631-640

    

  • Indirect CB~2 Receptor and Mediator-Dependent Stimulation of Human Whole-Blood Neutrophils by Exogenous and Endogenous Cannabinoids

    H. G. Kress, B. Kraft

    págs. 641-647

    

  • Prolonged Increase in the Sensitivity of the Posterior Ventral Tegmental Area to the Reinforcing Effects of Ethanol following Repeated Exposure to Cycles of Ethanol Access and Deprivation

    V. K. McQueen, Z. A. Rodd, R. L. Bell

    págs. 648-657

    

  • Methyllycaconitine Prevents Methamphetamine-Induced Effects in Mouse Striatum: Involvement of alpha7 Nicotinic Receptors

    C. Chipana, M. Perez-Sanchez, E. Escubedo

    págs. 658-667

    

  • Transcriptional Regulation of Activating Transcription Factor 3 Involves the Early Growth Response-1 Gene

    F. G. Bottone

    págs. 668-677

    

  • Fibrotic Lung Fibroblasts Show Blunted Inhibition by cAMP Due to Deficient cAMP Response Element-Binding Protein Phosphorylation

    S. Q. Sun, Xiaoqiu Liu, R. S. Ostrom

    págs. 678-687

    

  • Acute and Chronic Effects of the Incretin Enhancer Vildagliptin in Insulin-Resistant Rats

    B. F. Burkey

    págs. 688-695

    

  • Effect of Morphine on Deep Dorsal Horn Projection Neurons Depends on Spinal GABAergic and Glycinergic Tone: Implications for Reduced Opioid Effect in Neuropathic Pain

    Y.-P. Chen, S.-R. Chen

    págs. 696-703

    

  • Coformulated N-Octanoyl-glucosylceramide Improves Cellular Delivery and Cytotoxicity of Liposomal Doxorubicin

    G. A. Koning, R. J. Veldman

    págs. 704-710

    

  • Fenobam: A Clinically Validated Nonbenzodiazepine Anxiolytic Is a Potent, Selective, and Noncompetitive mGlu5 Receptor Antagonist with Inverse Agonist Activity

    R. H. P. Porter

    págs. 711-721

    

  • Effects of Phytoestrogens Genistein and Daidzein on Prostacyclin Production by Human Endothelial Cells

    Carlos Hermenegildo

    págs. 722-728

    

  • Prostanoids Secreted by Alveolar Macrophages Enhance Ionic Currents in Swine Tracheal Submucosal Gland Cells

    J. M. Farley, Huiling Liu, A. M. Mamoon

    págs. 729-739