Proceedings of the National Academy of Sciences of the United States of America

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  Año 2006, Número 6

  • Protein--protein interactions for cancer therapy

    Curtis C. Harris

    págs. 1659-1660

    

  • Lewy bodies

    Clifford W. Shults

    págs. 1661-1668

    

  • Profile of Alan M. Lambowitz

    Nick Zagorski

    págs. 1669-1671

    

  • Profile of George Oster

    Regina Nuzzo

    págs. 1672-1674

    

  • A method for determining the dependence of calcium oscillations on inositol trisphosphate oscillations

    D. I. Yule, Y. Bai, J. Sneyd, K. Tsaneva-Atanasova, M. J. Sanderson, V. Reznikov

    págs. 1675-1680

    

  • A fast response mechanism for insulin storage in crystals may involve kink generation by association of 2D clusters

    Peter G. Vekilov, Dimitra K. Georgiou

    págs. 1681-1685

    

  • Interaction of MEQ protein and C-terminal-binding protein is critical for induction of lymphomas by Marek's disease virus

    Pippa Hawes, Susan J. Baigent, Martin J. Allday, Jason P. Chattoo, Andrew C. Brown, Lawrence J. Petherbridge, Lorraine P. Smith, Venugopal Nair

    págs. 1687-1692

    

  • Selection of biocatalysts for chemical synthesis

    Bernard Witholt, Jan B. van Beilen, Stephan van Sint Fiet

    págs. 1693-1698

    

  • Zinc supplementation of young men alters metallothionein, zinc transporter, and cytokine gene expression in leukocyte populations

    Raymond K. Blanchard, Robert J. Cousins, Tolunay Beker Aydemir

    págs. 1699-1704

    

  • Crystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase

    Alejandro Buschiazzo, Armand Berneman, Wim Degrave, Pedro M. Alzari, Paola Minoprio, Alain Cosson, Christophe Grégoire, Nicolas Coatnoan, Nathalie Chamond, William Shepard, Maira Goytia, Francis Schaeffer

    págs. 1705-1710

    

  • Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D

    Christopher D. Lima, Jideofor Aniukwu, Michael S. Glickman, Jayakrishnan Nandakumar, Stewart Shuman

    págs. 1711-1716

    

  • Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change

    Ewen Gallagher, Michael Karin

    págs. 1717-1722

    

  • Manipulating phospholipids for crystallization of a membrane transport protein

    Shushi Nagamoni, Irina Smirnova, H. Ronald Kaback, Gill Verner, Lan Guan

    págs. 1723-1726

    

  • Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis

    Noriyuki Miyoshi, P. Boon Chock, Hammou Oubrahim, Earl R. Stadtman

    págs. 1727-1731

    

  • Insight into autoproteolytic activation from the structure of cephalosporin acylase: A protein with two proteolytic chemistries

    págs. 1732-1737

    

  • Determination of the geometric structure of the metal site in a blue copper protein by paramagnetic NMR

    D. Flemming Hansen, Jens J. Led

    págs. 1738-1743

    

  • Polyproline II conformation is one of many local conformational states and is not an overall conformation of unfolded peptides and proteins

    Joanna Makowska, Harold A. Scheraga, Lech Chmurzy¿ski, Adam Liwo, Jorge A. Vila, Katarzyna Bagi¿ska, Sylwia Rodziewicz-Motowid¿o

    págs. 1744-1749

    

  • Multiple events on single molecules: Unbiased estimation in single-molecule biophysics

    Daniel A. Koster, Nynke H. Dekker, Chris H. Wiggins

    págs. 1750-1755

    

  • Weighting of experimental evidence in macromolecular structure determination

    Wolfgang Rieping, Michael Nilges, Michael Habeck

    págs. 1756-1761

    

  • Prestressed F-actin networks cross-linked by hinged filamins replicate mechanical properties of cells

    J. H. Hartwig, D. A. Weitz, M. L. Gardel, F. Nakamura, J. C. Crocker, T. P. Stossel

    págs. 1762-1767

    

  • Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency

    R. de Cabo, J. Allard, H. Jamieson, G. López-Lluch, S. Hilmer, M. Zhu, M. V. Cascajo, B. Jones, P. Navas, N. Hunt, D. K. Ingram

    págs. 1768-1773

    

  • Integrins regulate VE-cadherin and catenins: Dependence of this regulation on Src, but not on Ras

    Julie Y.-S. Li

    págs. 1774-1779

    

  • Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone & receptor

    Fumihiko Furuya, John A. Hanover

    págs. 1780-1785

    

  • Chemosensing in Escherichia coil: Two regimes of two-state receptors

    Yigal Meir, Robert G. Endres, Ned S. Wingreen, Monica Skoge, Juan E. Keymer

    págs. 1786-1791

    

  • Immortalized keratinocyte lines derived from human embryonic stem cells

    James G. Rheinwald, Karen Easley, Shiro Iuchi, Howard Green, Sally Dabelsteen

    págs. 1792-1797

    

  • Transposable elements have contributed to thousands of human proteins

    Roy Britten

    págs. 1798-1803

    

  • Historical contingency and the purported uniqueness of evolutionary innovations

    Geerat J. Vermeij

    págs. 1804-1809

    

  • Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels

    Alexander Pertsemlidis, Saleemah Fahmi, Jonathan C. Cohen, Sophie Esmail, Helen H. Hobbs, Gloria L. Vega, Scott M. Grundy

    págs. 1810-1815

    

  • Suppression of gross chromosomal rearrangements by yKu7O-yKu8O heterodimer through DNA damage checkpoints

    Soma Banerjee, Stephanie Smith

    págs. 1816-1821

    

  • Development of CD4⁺ I cells expressing a nominally MHC class I-restricted I cell receptor by two different mechanisms

    Vinay S. Mahajan, Herman N. Eisen, Tam Nuygen, Phillip D. Holler

    págs. 1822-1827