Journal of Pharmacology and Experimental Therapeutics

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  Año 2006, Vol. 317, Número 1

  • Induction of Adenosine A~1 Receptor Expression by Pertussis Toxin via an Adenosine 5'-Diphosphate Ribosylation-Independent Pathway

    S. Jajoo, D. Mukherjea

    págs. 1-10

    

  • Induction of Renal 20-Hydroxyeicosatetraenoic Acid by Clofibrate Attenuates High-Fat Diet-Induced Hypertension in Rats

    H. Huang, H.-H. Chang, Y. Zhou

    págs. 11-18

    

  • Vascular Adhesion Protein-1 Plays an Important Role in Postischemic Inflammation and Neuropathology in Diabetic, Estrogen-Treated Ovariectomized Female Rats Subjected to Transient Forebrain Ischemia

    L. Salter-Cid, H.-L. Xu

    págs. 19-29

    

  • Effect of Subchronic Treatment of Memantine, Galantamine, and Nicotine in the Brain of Tg2576 (APPswe) Transgenic Mice

    M. M. Svedberg, C. Unger

    págs. 30-36

    

  • Peroxisome Proliferator-Activated Receptor gamma Down-Regulates Receptor for Advanced Glycation End Products and Inhibits Smooth Muscle Cell Proliferation in a Diabetic and Nondiabetic Rat Carotid Artery Injury Model

    Z. Zhou, M. Zhang, K. Wang

    págs. 37-43

    

  • S-Adenosyl-L-methionine Attenuates Hepatotoxicity Induced by Agonistic Jo2 Fas Antibody following CYP2E1 Induction in Mice

    A. I. Cederbaum, X. Wang

    págs. 44-52

    

  • Anti-Inflammatory Activity in Vitro and in Vivo of the Protein Farnesyltransferase Inhibitor Tipifarnib

    K.-T. A. Lai, X. Xue

    págs. 53-60

    

  • 3H-1,2-Dithiole-3-thione Targets Nuclear Factor kappaB to Block Expression of Inducible Nitric-Oxide Synthase, Prevents Hypotension, and Improves Survival in Endotoxemic Rats

    A. R. Karuri

    págs. 61-67

    

  • Alteration in Erythropoietin-Induced Cardioprotective Signaling by Postinfarct Ventricular Remodeling

    T. Miki, T. Miura

    págs. 68-75

    

  • Microarray Analysis of Mouse Ear Tissue Exposed to Bis-(2-chloroethyl) Sulfide: Gene Expression Profiles Correlate with Treatment Efficacy and An Established Clinical Endpoint

    J. F. Dillman

    págs. 76-87

    

  • Reciprocal Interaction of Serotonin and Neuronal Activity in Regulation of cAMP-Responsive Element-Dependent Gene Expression

    M. A. Mahgoub

    págs. 88-96

    

  • 9L Gliosarcoma Cell Proliferation and Tumor Growth in Rats Are Suppressed by N-Hydroxy-N'-(4-butyl-2-methylphenol) Formamidine (HET0016), a Selective Inhibitor of CYP4A

    J. D. Fenstermacher, R. J. Roman, M. Guo

    págs. 97-108

    

  • Cell Death Mechanism and Protective Effect of Erythropoietin after Focal Ischemia in the Whisker-Barrel Cortex of Neonatal Rats

    L. Wei, B. H. Han

    págs. 109-116

    

  • Modeling Glucocorticoid-Mediated Fetal Lung Maturation: I. Temporal Patterns of Corticosteroids in Rat Pregnancy

    M. N. Samtani, N. A. Pyszczynski

    págs. 117-126

    

  • Modeling Glucocorticoid-Mediated Fetal Lung Maturation: II. Temporal Patterns of Gene Expression in Fetal Rat Lung

    N. A. Pyszczynski, M. N. Samtani

    págs. 127-138

    

  • Probing Ligand-Specific Histamine H~1- and H~2-Receptor Conformations with N^G-Acylated Imidazolylpropylguanidines

    P. Ghorai, S.-X. Xie

    págs. 139-146

    

  • Pharmacological Characterization of (E)-N-(4-Fluorobut-2-enyl)-2beta-carbomethoxy-3beta-(4'-tolyl)nortropane (LBT-999) as a Highly Promising Fluorinated Ligand for the Dopamine Transporter

    S. Chalon

    págs. 147-152

    

  • Resistance to the Antineoplastic Agent Gallium Nitrate Results in Marked Alterations in Intracellular Iron and Gallium Trafficking: Identification of Novel Intermediates

    C. R. Chitambar, Y. S. Rahmanto, D.R. Richardson, N. P. Davies

    págs. 153-162

    

  • Hypocretin (Orexin) Receptor Subtypes Differentially Enhance Acetylcholine Release and Activate G Protein Subtypes in Rat Pontine Reticular Formation

    R. Bernard

    págs. 163-171

    

  • Adenosine Inhibits Tumor Necrosis Factor-alpha Release from Mouse Peritoneal Macrophages via A~2~A and A~2~B but Not the A~3 Adenosine Receptor

    L. M. Kreckler

    págs. 172-180

    

  • In Vivo Characterization of the Novel Imidazopyridine BYK191023 [2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine], a Potent and Highly Selective Inhibitor of Inducible Nitric-Oxide Synthase

    M. D. Lehner

    págs. 181-187

    

  • Inhibition of Phosphodiesterase 5 Selectively Reverses Nitrate Tolerance in the Venous Circulation

    H. A. Dunkerley, J. D. MacPherson, T. D. Gillespie

    págs. 188-195

    

  • Differential Effects of Cocaine on Firing Rate and Pattern of Dopamine Neurons: Role of alpha~1 Receptors and Comparison with L-Dopa and Apomorphine

    Y. Zhou, B. S. Bunney

    págs. 196-201

    

  • Ubiquitin-Dependent Degradation of p53 Protein Despite Phosphorylation at Its N Terminus by Acetaminophen

    Y.-S. Lee

    págs. 202-208

    

  • Modeling Drug- and System-Related Changes in Body Temperature: Application to Clomethiazole-Induced Hypothermia, Long-Lasting Tolerance Development, and Circadian Rhythm in Rats

    S. A. G. Visser

    págs. 209-219

    

  • Peripherally Mediated Antinociception of the mu-Opioid Receptor Agonist 2-[(4,5alpha-Epoxy-3-hydroxy-14beta-methoxy-17-methylmorphinan-6beta-yl)amino]acetic Acid (HS-731) after Subcutaneous and Oral Administration in Rats with Carrageenan-Induced Hindpaw Inflammation

    I. Bileviciute-Ljungar

    págs. 220-227

    

  • Noninvasive Mapping of Reactive Oxygen Species by in Vivo Electron Spin Resonance Spectroscopy in Indomethacin-Induced Gastric Ulcers in Rats

    K. Yasukawa, H. Utsumi

    págs. 228-235

    

  • Rotigaptide (ZP123) Prevents Spontaneous Ventricular Arrhythmias and Reduces Infarct Size During Myocardial Ischemia/Reperfusion Injury in Open-Chest Dogs

    J. K. Hennan, G. A. Morgan, R. E. Swillo

    págs. 236-243

    

  • A Novel, Selective, and Orally Available Antagonist for CC Chemokine Receptor 3

    T. Morokata

    págs. 244-250

    

  • Fatty Acid Amide Hydrolase (-/-) Mice Exhibit an Increased Sensitivity to the Disruptive Effects of Anandamide or Oleamide in a Working Memory Water Maze Task

    B. F. Cravatt, S. A. Varvel

    págs. 251-257