Nature: International weekly journal of science

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  Año 2015, Vol. 527, Número Extraordinario 7578. Texto Completo Ejemplar

  • Breast cancer

    Chris Woolston

    • Texto completo

    págs. 101-101

    

  • A tumour through time: Breast cancer, one of the most common and deadly malignancies, has undoubtedly plagued humans since the dawn of our species. The history of the fight against the disease is one of lurching progress against a backdrop of misery. But recent decades have seen greatly improved treatments and increased survival. By Will Tauxe.

    Will Tauxe

    • Texto completo

    págs. 102-103

    

  • Perspective: The risks of overdiagnosis: Screening mammograms catch some cancers that pose little threat. Alexandra barratt explains why she may decide to skip the scans.

    Alexandra Barratt

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    págs. 104-104

    

  • Immunology: Another shot at cancer: Targeting the immune system to fight breast cancer was all but dismissed in the 1990s, but the strategy is making a big comeback with the possibility of a breast-cancer vaccine.

    Charles Schmidt

    • Texto completo

    págs. 105-107

    

  • Genetics: Big hopes for big data: Technology is allowing researchers to generate vast amounts of information about tumours. The next step is to use this genomic data to transform patient care.

    Jill U. Adams

    • Texto completo

    págs. 108-109

    

  • Medicine: Eyes on the target: A push to expand the success of a pair of antibody-based drugs is buying some women years of freedom from breast cancer.

    Michael Eisenstein

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    págs. 110-112

    

  • Molecular biology: Marked progress: Reliable markers could eliminate surgery and radiation therapy for many women diagnosed with a type of cancer that often does not progress beyond its non-invasive form.

    Hannah Hoag

    • Texto completo

    págs. 114-115

    

  • Genetics: Relative risk: Mutations in brca genes predispose women to cancer, but outside influences shape the ultimate risk.

    Moises Velasquez Manoff

    • Texto completo

    págs. 116-117

    

  • Screening: Don'T look now: Mammogram screenings are an established part of women'S health care, but are they more trouble than they are worth?

    Emily Sohn

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    págs. 118-119

    

  • Breast cancer: 4 big questions: Although treatments for breast cancer have come a long way over the past few generations, researchers are still puzzling over some tough questions.

    Chris Woolston

    • Texto completo

    págs. 120-120

    

  • Brain disorders across the lifespan

    Roger I. Glass

    • Texto completo

    págs. 150-150

    

  • Brain and other nervous system disorders across the lifespan — global challenges and opportunities

    Donald Silberberg, Nalini P. Anand, Kathleen Michels, Raj N. Kalaria

    • Resumen
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    págs. 151-154

    

  • Reducing neurodevelopmental disorders and disability through research and interventions

    Michael J. Boivin, Angelina M. Kakooza, Benjamin C Warf, Leslie L. Davidson, Elena L. Grigorenko

    • Resumen
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    págs. 155-160

    

  • A focus on adolescence to reduce neurological, mental health and substance-use disability

    Leslie L. Davidson, Elena L. Grigorenko, Michael J. Boivin, Elizabeth Rapa, Alan Stein

    • Resumen
    • Texto completo

    págs. 161-166

    

  • Nervous system disorders across the life course in resource-limited settings

    Gretchen L Birbeck, Ana-Claire Meyer, Adesola Ogunniyi

    • Resumen
    • Texto completo

    págs. 167-171

    

  • Global research challenges and opportunities for mental health and substance-use disorders

    Florence Baingana, Mustafa Al'Absi, Anne E. Becker, Beverly Pringle

    • Resumen
    • Texto completo

    págs. 172-177

    

  • Global research priorities for infections that affect the nervous system

    Chandy C John, Hélène Carabin, Silvia M. Montano, Paul Bangirana, Joseph R Zunt, Phillip K. Peterson

    • Resumen
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    págs. 178-186

    

  • A global perspective on the influence of environmental exposures on the nervous system

    Desire Tshala Katumbay, Jean-Claude Mwanza, Diane S. Rohlman, Gladys E. Maestre, Reinaldo B. Oriá

    • Resumen
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    págs. 187-192

    

  • Global neurotrauma research challenges and opportunities

    Andrés M. Rubiano, Nancy Carney, Randall Chesnut, Juan Carlos Puyana

    • Resumen
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    págs. 193-197

    

  • Regional research priorities in brain and nervous system disorders

    Vijayalakshmi Ravindranath, Hoang-Minh Dang, Rodolfo G. Goya, Hader Mansour, Vishwajit L. Nimgaonkar, Vivienne Ann Russell, Ju Xin

    • Resumen
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    págs. 198-206

    

  • Building global capacity for brain and nervous system disorders research

    Linda B. Cottler, Joseph Zunt, Bahr Weiss, Ayeesha Kamran Kamal, Krishna Vaddiparti

    • Resumen
    • Texto completo

    págs. 207-213