Science

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  Año 2016, Vol. 351, Número 6280

  • Survey of variation in human transcription factors reveals prevalent DNA binding changes

    Luis A. Barrera, Anastasia Vedenko, Jesse V. Kurland, Julia M. Rogers

    • Resumen

    págs. 1450-1454

    

  • Activation of proto-oncogenes by disruption of chromosome neighborhoods

    Denes Hnisz, Abraham S. Weintraub, Daniel S. Day, Anne Laure Valton

    • Resumen

    págs. 1454-1458

    

  • HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

    Joseph G. Jardine, Daniel W. Kulp, Colin Havenar Daughton, Anita Sarkar

    • Resumen

    págs. 1458-1463

    

  • Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

    Nicholas McGranahan, Andrew J. S. Furness, Rachel Rosenthal, Sofie Ramskov

    • Resumen

    págs. 1463-1469

    

  • Direct observation of proton pumping by a eukaryotic P-type ATPase

    Salome Veshaguri, Sune M. Christensen, Gerdi C. Kemmer, Garima Ghale

    • Resumen

    págs. 1469-1473

    

  • Lessons from a bridge generation

    Rosalind Segal

    págs. 1494-1494