Clinical & translational oncology

• 

  Año 2024, Vol. 26, Número 10

  • REVIEW ARTICLE

    • Heterogeneity and interplay: the multifaceted role of cancer‑associated fibroblasts in the tumor and therapeutic strategies

      Qiaoqiao Liu, Fei Yao, Liangliang Wu, Tianyuan Xu, Jintong Na, Zhen Shen, Xiyu Liu, Wei Shi, Yongxiang Zhao, Yuan Liao

      • Resumen

      págs. 2395-2417

      

    • Akkermania muciniphila: a rising star in tumor immunology

      Leihan Wang, Dong Tang

      • Resumen

      págs. 2418-2430

      

    • Recent updates in the therapeutic uses of Pembrolizumab: a brief narrative review

      Vítor Silva, Cristiano Matos

      • Resumen

      págs. 2431-2443

      

    • Prostate cancer biomarkers: from early diagnosis to precision treatment

      Versha Dahiya, Sanjana Hans, Ruchi Kumari, Gargi Bagchi

      • Resumen

      págs. 2444-2456

      

  • RESEARCH ARTICLE

    • State of open science in cancer research

      Cristina Rius, Yiming Liu, Andrea Sixto Costoya, Juan Carlos Valderrama Zurián, Rut Lucas Domínguez

      • Resumen

      págs. 2457-2465

      

    • An overview of current research on cancer stem cells: a bibliometric analysis

      Xueyang Zhang, Wenbo Du, Xizhi Huang, Haoting Zhong, Ning Hu

      • Resumen

      págs. 2466-2478

      

    • Exploration of efficacy of different therapy regimens for advanced NSCLC patients with KRAS mutation in the first‑line treatment

      Ke Wang, Manyi Xu, Yanhua Wang, Yue Hao, Chunwei Xu, Zhengbo Song

      • Resumen

      págs. 2479-2487

      

    • Comparison of efficacy and safety of PD‑1/PD‑L1 combination therapy in first‑line treatment of advanced NSCLC: an updated systematic review and network meta‑analysis

      Yanqing Yang, Wei Chen, Lixian Dong, Pengfei Gao, Lian Duan

      • Resumen

      págs. 2488-2502

      

    • Efficacy and safety analysis of immunotherapy in non‑small cell lung cancer patients with MET alterations

      Yanhua Wang, Manyi Xu, Jing Xiang, Yue Hao, Jingwen Wei, Keda Shao, Zhengbo Song

      • Resumen

      págs. 2503-2512

      

    • Clinical difference on the variants and co‑mutation in a Chinese cohort with ALK‑positive advanced non‑small cell lung cancer

      Ying Fu, Qing Liu, Xiaohan Wang, Liangchao Sun, Xiao Han Xu, Xue Meng

      • Resumen

      págs. 2513-2521

      

    • Peripheral NK cells identified as the predictor of response in extensive‑stage small cell lung cancer patients treated with first‑line immunotherapy plus chemotherapy

      Yanan Cui, Yanping Chen, Xiubao Ren, Peiyan Zhao, Shuang Li, Ying Chen

      • Resumen

      págs. 2522-2530

      

    • HER2/neu 655 polymorphism, trastuzumab‑induced cardiotoxicity, and survival in HER2‑positive breast cancer patients

      Isabel Blancas López-Barajas, Marina Linares Rodríguez, Celia Martín Bravo, Celia Gómez Peña, Fernando Rodríguez Serrano

      • Resumen

      págs. 2531-2540

      

    • An analysis of the association between breast density and body mass index with breast cancer molecular subtypes in early breast cancer: data from a Spanish population

      Isabel Calvo Plaza, Marta González Rodríguez, Laura G. García Estévez, Fernando Neria, Isabel Gallegos, Lourdes García, Rosa Sánchez Gómez, Silvia Pérez, María Fernanda Arenas

      • Resumen

      págs. 2541-2548

      

    • High MAL2 expression predicts shorter survival in women with triple‑negative breast cancer

      Jędrzej Borowczak, Marek Zdrenka, Krzysztof Szczerbowski, Mateusz Maniewski, Hanna Andrusewicz, Joanna Łysik Miśkurka, Łukasz Szylberg, Weronika Socha, Karol Gostomczyk, Magdalena Bodnar, Tomasz Nowikiewicz

      • Resumen

      págs. 2549-2558

      

    • Comparative effectiveness of first‑line systemic treatments for metastatic castration‑resistant prostate cancer: a systematic review and network meta‑analysis

      Jiahuan Ai, Liuying Jian, Xiaoqin Wen, Xiaotong Huo, Xuanyi Yang, Jie Jiang, Tiantian Zhang

      • Resumen

      págs. 2559-2571

      

    • Access to melanoma drugs in Spain: a cross‑sectional survey

      María González Cao, Ana Drozdowskyj, Teresa Puértolas Hernández, José Luis Manzano Mozo, Cayetana Maldonado Seral, Oriol Yélamos, Miguel Ángel Berciano Guerrero, Pablo Cerezuela Fuentes, Juan Martin Liberal, Eva Muñoz Couselo, E. Espinosa Arranz, Alfonso Berrocal Jaime, Ainara Soria, Iván Márquez Rodas, Salvador Martín Algarra, María Quindós Varela, Susana Puig Sardá

      • Resumen

      págs. 2572-2583

      

    • Determining individual suitability for neoadjuvant systemic therapy in breast cancer patients through deep learning

      Enzhao Zhu, Tianyu Ji, Jianmeng Dai, Jiayi Wang, Qianyi Yu, Qiuyi Lu, Linmei Zhang, Yixian Liu, Ruichen Tang, Kai Chen, Chunyu Hu, Zisheng Ai

      • Resumen

      págs. 2584-2593

      

    • The effect of hyperbaric oxygen therapy in head and neck cancer patients with radiation induced dysphagia—a systematic review

      Bahareh Bakhshaie Philipsen, Malene Korsholm, Max Rohde, Christian Godballe, Irene Wessel, Lone Forner, Jørgen Johansen

      • Resumen

      págs. 2594-2600

      

    • Development and validation of a nomogram to predicting the efficacy of PD‑1/PD‑L1 inhibitors in patients with nasopharyngeal carcinoma

      Yao Chen, Dubo Chen, Ruizhi Wang, Shuhua Xie, Hao Huang, Xueping Wang

      • Resumen

      págs. 2601-2607

      

    • Treatment benefit of electrochemotherapy for superficial squamous cell carcinoma: a systematic review and single‑arm meta‑analysis

      Zhuoxia Wu, Lingfeng Pan, Lianbo Zhang, Chen Tao, Liehao Yang, Yan Yan

      • Resumen

      págs. 2608-2617

      

    • Pancreatic ductal adenocarcinoma: exploring clinicopathological trends and racial disparities in a comprehensive U.S. population‑based study

      Abdul Qahar Khan Yasinzai, Bisma Tareen, Nimra Jamil, Hafeez Ullah, Muhammad Raza, Amin Ullah Khan, Katharine Tracy, Marjan Khan, Abdul Waheed, Feroze Sidhwa, Subhasis Misra, Nabin R. Karki, Nagla Abdel Karim, Dauod Arif, Ludimila Cavalcante, Asad Ullah

      • Resumen

      págs. 2618-2628

      

    • How appropriate is treating patients diagnosed with advanced esophageal cancer with anticancer drugs? A multicenter retrospective cohort Spanish study

      Marilina Santero, Carolina Requeijo, Maria Jesus Quintana, X. Bonfill, Iratxe Urreta Barallobre, Dulce Rodríguez Mesa, David Bottaro Parra, Ismael Macías Declara, Carles Pericay Pijaume, Natalie Farina, Jesus Manuel Blanco, Laura Punti, Maria Angeles Nava

      • Resumen

      págs. 2629-2639

      

    • Sequential RAS mutations evaluation in cell‑free DNA of patients with tissue RAS wild‑type metastatic colorectal cancer: the PERSEIDA (Cohort 2) study

      Manuel Valladares Ayerbes, María José Safont, E. González Flores, Pilar García Alfonso, Enrique Aranda Aguilar, Ana María López Muñoz, Esther Falcó Ferrer, Lluís Cirera Nogueras, Nuria Rodríguez Salas, Jorge Aparicio Urtasun, Marta Llanos Muñoz, Paola Patricia Pimentel Cáceres, Oscar Alfredo Castillo Trujillo, María del Rosario Vidal Tocino, Mercedes Salgado Fernández, Antonieta Salud, Bartomeu Massuti Sureda, Rocío García Carbonero, María Ángeles Vicente Conesa, Ariadna Lloansí

      • Resumen

      págs. 2640-2651

      

    • Clinical efficacy of lenvatinib, trans‑arterial chemoembolization, and PD‑1/L1 inhibitors in advanced hepatocellular carcinoma: a systematic review and network meta‑analysis

      YiFeng Liang, LiMing Gan, DeJin Zeng, LangHua Lin, ZheKun Xiong, FangLian Liao, A Ling Wang

      • Resumen

      págs. 2652-2664

      

    • Upregulation of NPC1 and its association with poor prognosis in gastric cancer

      Wei Tang, Jiahua Huang, Guanghua Li, Zhihao Zhou, Zhixiong Wang

      • Resumen

      págs. 2665-2673

      

    • Assessing clinical pathological characteristics and gene expression patterns associated with hepatoid adenocarcinoma of the stomach

      Dong Feng Ge, Kun Wang, Ying Li, Su Nan Wang, Xing Hai Liao, Chao Ya Zhu, Bo Jiang

      • Resumen

      págs. 2674-2684

      

    • External validation of the RIETE and SOME scores for occult cancer in patients with venous thromboembolism: a multicentre cohort study

      Ana Isabel Franco Moreno, Nuria Muñoz Rivas, Juan Torres Macho, Ana Bustamante Fermosel, Nuria Alfaro Fernández, J. Bascuñana Morejón de Girón, Paloma Agudo Blas, Cristina de Ancos Aracil, Justo Ruiz Ruiz, José Manuel Ruiz Giardín, Elena Madroñal Cerezo

      • Resumen

      págs. 2685-2692

      

    • Unveiling sex‑based geographical disparities in myelodysplastic syndrome mortality trends in Spain (1999–2022)

      Reyes María Martín Rojas, Lucía Cayuela Rodríguez, Francisco Martín Domínguez, Aurelio Cayuela Domínguez

      • Resumen

      págs. 2693-2700

      

    • Comprehensive pan‑cancer analysis reveals prognostic implications of TMEM92 in the tumor immune microenvironmen

      Zheng Wu, Teng Pan, Wen Li, Yue Zhang, Sheng hu Guo, Ya Liu, Lei Zhang, Zhi yu Wang

      • Resumen

      págs. 2701-2717

      

    • The cuproptosis‑related gene UBE2D2 functions as an immunotherapeutic and prognostic biomarker in pan‑cancer

      Yao Fei, Xueliang Zuo, Danping Cao, Runyu Dong, Yanna Li, Zhixiong Wang, Peng Gao, Menglin Zhu, Xiaoming Wang, Juan Cai

      • Resumen

      págs. 2718-2737