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Resumen de Quantitative central corneal anatomy and anaesthetic eye drops effects: comparison between 0.4% oxybuprocaine and a combination of 0.1% tetracaine and 0.4% oxybuprocaine.

Isabel Asensio Romero, José María Palanca Sanfrancisco, Juan Alberto Sanchis Gimeno, Manuel Granell Gil, L. Alonso, M.S. Rahhal, Francisco Martínez Soriano

  • We aimed to analyse the changes in central corneal thickness values following the instillation of 0.4% oxybuprocaine eye drops and following a combination of 0.1% tetracaine and 0.4% oxybuprocaine eye drops. Orbscan pachymetry (Orbscan II Corneal Topography System; Orbscan, Inc., Salt Lake City, UT, USA) was carried out before and three minutes after the instillation of 0.4% oxybuprocaine eye drops, and before and three minutes after the instillation of a combination of 0.1% tetracaine and 0.4% oxybuprocaine eye drops in 35 healthy subjects (n=35; aged 20-30 years). After the instillation of 0.4% oxybuprocaine eye drops there was a mean increase in central corneal thickness of 25±11 microns. After the combination of 0.1% tetracaine and 0.4% oxybuprocaine eye drops it rose to 48±20 microns. The combination of 0.1% tetracaine and 0.4% oxybuprocaine anaesthetic eye drops causes higher increases in central corneal thickness values than 0.4% oxybuprocaine eye drops.


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