Resumen de Stomathologycal lesions in HIV-1 reactive patients: comparison of proportion in two independent populations

S. Fonio, S. Micinquevich, Zulema Casariego

• Prevalence of stomathologycallesions notably changed after highly active antiretroviral therapy (HMRT). This event is testify by international scientific Iiterature. Purpose of this study is to diagnose and to register by statistic analysis HIV oral manifestations comparing in two independent populations.

  Study Desígn: Stomathologycallesions were diagnosticated in HIV/AIDS patients by the same oral specialist. They were attended in our Service during two observation periodes (OP): 1988-1996 and 1997-2004, 12th hours/week and 6 hours/week respectively. Confirmation of c1inic diagnoses was made by citology, histopathology, immunohistochemistry and PCR, according to each pathogenesis. Both time's periodes were compare for each pathology by "Comparison Method per Proportions" (independent munsters) with a signification level: p<0.05. Data were processed with EPIDAT, version 3 (YUNTA OF GALlCIA- OPS/OMS).

  Results: OP1 =2873 pathologies, OP2=520. Comparison in both OPs was: statistical signification p<0.05:

  Eritematous and Pseudomembranous Candidiasis (EC),PSC), Hairy leukoplakia (HL), Recidivant aphtous ulcers (RAU), Angular Cheilitis (ACH), PapilIoma Human Virus (HPV), Herpes Virus (HV), and Non-Hodking Limphoma (NHL). Withow statistic significance: Acute necrotizing gingivitis (ANUG) and Kaposi Sarkoma. (KS). In the second Op, RAU, HPV and HSV shawed significantIy statistic differences, specially RAU with 44,2% of prevalence. Conc/usions: 1) Our results could confirm declining prevalence of most of oral manifestations of HIV infection in HAART era. 2) We stand out the significance of RAU, HPV and HSV prevalences in the last period of time.