Resumen de Síntomas depresivos en el embarazo y factores asociados en pacientes de tres instituciones de salud de la ciudad de México

Claudia Navarro Guzmán, Laura Navarrete, Mª Asunción Lara Cantú, Alejandra Cabrera, Jesús Almanza

• español

  Antecedentes La depresión es una condición frecuente en el embarazo, por lo menos tan frecuente como en las mujeres que no están embarazadas. Estudios sobre su prevalencia por medio de entrevistas estructuradas muestran tasas de dos a 21% de depresión mayor y las escalas de síntomas arrojan cifras de entre ocho y 31%. En México la prevalencia se ha estimado en 22% con base en una escala de autorreporte. Entre los factores de riesgo de depresión en el embarazo se encuentran historia previa de depresión, separación de los padres en la infancia, ser madre soltera, no desear estar embarazada, falta de apoyo social y baja escolaridad. Debido a las consecuencias que tiene la depresión sobre el proceso del embarazo y a los pocos estudios que existen en nuestro país a este respecto, el objetivo del trabajo fue investigar la prevalencia de sinto-matología depresiva en mujeres embarazadas, así como los factores de riesgo asociados a la misma.

  Material y métodos Se entrevistó en salas de espera a 300 mujeres embarazadas que buscaban atención prenatal, en tres instituciones (un hospital de tercer nivel, un centro de salud y una clínica de especialidades de la mujer). El instrumento incluyó una escala de depresión (CES-D) y los siguientes factores de riesgo: síntomas previos de depresión, separación de los padres antes de los 11 años, posible depresión y consumo problemático de alcohol en los padres, embarazo no planeado y apoyo social.

  Resultados De las entrevistadas 30.7% mostró sintomatología depresiva significativa (CES-D >16) y 59% mencionó haber padecido estos síntomas en el pasado. Algún nivel de discapacidad en el último mes fue manifestado por 19% de quienes mencionaron haber presentado sintomatología el mes anterior. La media de días en que no pudieron hacer sus actividades diarias, trabajar o asistir a la escuela fue de 11.21 (DE = 10.68), con un rango de uno a 30 días. Es importante mencionar que 7 mujeres (21.2%) dijeron haber dejado sus actividades por este motivo todos los días del mes anterior. En cuanto a la ideación suicida alguna vez en la vida, la mitad dijo haber pensado mucho en la muerte, una cuarta parte haber deseado morir, cerca de una quinta parte tuvo la intención de quitarse la vida y 7.7% se ha herido con el fin de quitarse la vida. Durante el último mes, las frecuencias de estas conductas disminuyeron considerablemente a casi cero y sólo "pensar mucho en la muerte" fue frecuente (18%).

  Las variables que se asociaron con dichos síntomas fueron: síntomas previos de depresión (t = - 4.40, p > 0.000); separación del padre antes de los 11 años (t = -2.68; p > 0.008); posible depresión en la madre (t = -3.24; p > 0.001), posible depresión en el padre (t = -2.41, p > 0.016), consumo problemático de alcohol en el padre (t = -2.23, p > 0.040); embarazo no planeado (t = -2.43, p > 0.015), falta de apoyo social emocional (t = 2.87, p >0.004) y falta de apoyo social práctico (t = 2.94, p > 0.005). La evaluación de un modelo incluyendo estos factores sobre la sinto-matología depresiva mediante regresión logística utilizando el método por pasos, mostró que las siguientes variables fueron significativas: la posible depresión en la madre, que incrementa el riesgo de presentar depresión en el embarazo en 0.8 veces, la sintomatología depresiva previa, que lo aumenta en 1.08 veces, la falta de apoyo social práctico, que lo incrementa 1.71 veces y no tener pareja, con un incremento de 1.51 veces.

  Conclusiones Casi una tercera parte de las embarazadas mostró sintomatología depresiva significativa la cual se asoció a diversos factores psicosociales de riesgo previamente documentados en la bibliografía internacional. Existen similitudes en la depresión durante el embarazo y en otros momentos de la vida, pero en este periodo tiene particular importancia debido a las nuevas demandas que en este momento enfrenta la mujer y a los efectos adversos que la depresión tiene sobre el desarrollo del embarazo, así como al elevado riesgo de presentar depresión en el posparto.

• English

  Background Depression is a frequent condition in pregnancy, at least as frequent as it is among non-pregnant women. Studies on its prevalence show rates from 2% to 21% of major depression and 8% to 31% of depressive symptomatology. In Mexico, a prevalence of 22% has been estimated on the basis of a self-report scale. Risk factors for depression in pregnancy include previous history of depression, parental separation during childhood, single mother-hood, not wishing to be pregnant, lack of social support and low educational attainment.

  Objective Due to the consequences of depression on pregnancy and to the scarce studies available in Mexico, the aim of this study was to examine the presence of depression in pregnant women as well as the risk factors associated with the latter.

  Material and methods Three hundred pregnant women receiving ante-natal care were interviewed in the waiting rooms of three institutions (one third level hospital, a health center and a clinic specializing in women). The instrument included a scale of depression (CES-D) and the following risk factors: previous depression symptoms, parental separation before the age of 11, possible depression and problem-atic alcohol consumption in expectant motliers parents, unplanned pregnancy and lack of social support.

  Results A total of 30.7% of the interviewees showed significant depressive symptomatology (CES-D > 16). Fifty-nine percent mentioned having suffered from depressive symptomatology in the past. Some degree of disability in the past month was reported by 19% of those that mentioned depression symptoms. The mean number of days they stopped performing their everyday activities was 11.21 (SD = 10.68) with a range of 1 to 30 days. Seven women (21.2%) stated that they could not engage in their activities because of their depression every single day of the past month. As for suicidal ideation at any time in their lives, the following symptoms were displayed: half said that they had thought a great deal about death, a quarter said that they had wanted to die, nearly a fifth had intended to take their own life and 7.7% had injured themselves in order to take their own lives. During the previous month, the frequency of these behaviors had considerably declined, almost to zero, and only "thinking frequently about death" was common (18%).

  The variables associated with depression symptoms (CES-D) were: previous symptoms of depression (t = -4-40, p > 0.000), separation from the father before the age of 11 (t = -2.68; p > 0.008), possible depression in mother (t = -3.24, p > 0.001), possible depression in father (t = -2.41, p > 0.016), problematic alcohol consumption in father (t= -2.23, p > 0.040), unplanned pregnancy (t=-2.43, p>0-015), lack of emotional social support (t = 2.87, p > 0.005) and lack of practical social support (t = 2.94, p > 0.005). The evaluation of a risk model of these factors on depressive symptomatology through logistic regression (with the step-by-step method) showed that the following variables were significant: possible depression in the mother (of the expec-tant mother) which increases the risk of displaying depression in pregnancy 0.8 times, previous depressive symptomatology, which increases it 1.08 times, lack of practical social support, which increases it 1.71 times and not having a partner, which increases it 1.51 times.

  Discussion and conclusions The results, as regards mental health, showed that depressive symptoms occured in nearly a third of pregnant women; this percentage is higher than the 22% found in Mexico in previous studies. Although this symptomatology does not necessarily meet the criteria for major depression, it has been considered to be of sufficient clinical importance, as it has been associated with disability, psychiatric and physical co-morbidity; demand for treat-ment for and risk of future depression and in this case, with post-partum depression. A fifth of the subjects displayed more serious symptomatology in terms of disability, as the women mentioned not being able to engage in their everyday activities, working or studying. The mean number of days in which they were unable to carry out their activities was eleven during the previous month. This data suggests that this population with greater pathology should be detected and referred for specialized mental care by antenatal care services. Suicidal ideation during the previous month decreased considerably, in comparison with that reported at any time in theit lives, which agrees with reports that state that self-damaging behaviors and suicide attempts tend to be very low during pregnancy.

  As for pathological antecedents, 59% considered that they had suffered from depressive symptomatology in the past, in addition to having experienced suicidal ideation to varying degrees. It is significant that nearly 8% had previously attempted suicide. Both, previous depressive symptomatology and suicidal ideation in the past, were associated with current depression symptoms in the expectant mother, as has been reported in other countries.

  Unplanned pregnancy was also related to depression (CES-D). As literature suggests, not wishing to be pregnant is related to this disorder and although not planning a pregnancy is not synonymous with not wishing for it, according to these data, lack of planning also increases depressive symptoms.

  Among childhood situations, parental separation or loss of the father before the age of 11 was a significant variable as regards symptomatology in pregnancy; this was similar to what other authors have reported. Separation from the mother was not related to these symptoms, contrary to what other studies have reported in both pregnant and non-pregnant women. Adversity in childhood in the form of parents' mental pathology or substance use has been associated with depression among the general population. The results obtained here show a significant relationship between problematic alcohol consumption in the father and possible depression in the mother or father -as perceived by the interviewee herself- and depression symptoms in the expectant mother.

  During pregnancy and above all, post-partum, women have a real need to receive both emotional and practical support. This study, like others showed that the lack of this support increased the risk of depression.

  The construction of a model with some of these variables showed that being a single or divorced mother, having had a mother who may have been depressed, having displayed depressive symptoms in the past and the lack of practical support increased the risk of depressive symptomatology.

  By way of a conclusion, one can say that although there are similarities between depression in pregnancy and at other moments in women's lives, its presence during this period is particu-larly important due to the new demands the woman has to cope with and the adverse effects it has on the development of pregnancy, and the high risk of experiencing depression during the post-partum. Designing intervention programs for expectant mothers could have an enormous effect on improving the mental health of mothers and their babies, a reason why it is important to take into account the risk factors described in this study.