Objective: According to the self-medication hypothesis, schizophrenic patients would abuse psychoactive substances to get a relief from their negative symptoms. Different studies in dual diagnosis schizophrenia have not been conclusive. The authors compared positive, negative and general symptomatology between schizophrenic patients with and without lifetime psychoactive substances abuse.
Methodology: Patients with substances abuse (n = 20), without substances abuse (n = 20) with schizophrenia disorder (DSM-IV criteria) were assessed with the PANSS scale. The variables were studied by using analyses of variance (ANOVA).
Results: The schizophrenic patients with psychoactive substances abuse experience fewer negative symptoms assessed with the PANSS negative symptoms subscale (p < 0,001) compared with schizophrenics patients without psychoactive substances abuse.
Conclusions: The schizophrenic patients with dual diagnosis experience fewer negative symptoms than abstinent schizophrenic patients.
Methodology: Patients with substances abuse (n = 20), without substances abuse (n = 20) with schizophrenia disorder (DSM-IV criteria) were assessed with the PANSS scale. The variables were studied by using analyses of variance (ANOVA).
Results: The schizophrenic patients with psychoactive substances abuse experience fewer negative symptoms assessed with the PANSS negative symptoms subscale (p < 0,001) compared with schizophrenics patients without psychoactive substances abuse.
Conclusions: The schizophrenic patients with dual diagnosis experience fewer negative symptoms than abstinent schizophrenic patients.
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