Introduction: Vaginal adenosis is characterized by the presence of glandular tissue or its secretory products in the vaginal wall.
Case report: We report 2 cases of vaginal adenosis not associated with diethylstilbestrol exposure or any other apparent causes in 2 women aged 14 and 76 years old.
Discussion: Two groups of women are know to develop vaginal adenosis. In the first 'congenital' group, there is proliferation of the remnant Mullerian epithelium in the vagina due to in utero diethylstilbestrol exposure. In the second 'acquired' group, the following causes have been proposed: a) trauma and continuous inflammation of the vaginal mucosa (due to the use of CO2 laser, 5-fluoracyl, sanitary products or chronic pessary use); b) sex hormones; and c) idiopathic.
In both the congenital and acquired groups,there is an increased risk of developing vaginal adenocarcinona. Therefore, prompt diagnosis by monitoring lesions is essential.
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