Genes in Context: Probing the Genetics of Fracture Resistance.

• Autores: Neil A. Sharkey, Dean H. Lang
• Localización: Exercise and sport sciences reviews: a quarterly publication of the American College of Sports Medicine, ISSN 0091-6331, Vol. 35, Nº. 3, 2007, págs. 86-96
• Idioma: inglés
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• Resumen

  • Fracture resistance is a complex trait dictated by bone volume, shape, internal architecture, and material performance of the calcified tissue itself, all of which may be influenced by a large number of different genetic and environmental processes. Quantitative Trait Loci analyses provide a sobering picture of this system and illustrate the importance of considering genes in context.