Altered Mechanisms of Vasodilation in Aged Human Skin

• Autores: Lacy A. Holowatz, Caitlin S. Thompson Torgerson, W. Larry Kenney
• Localización: Exercise and sport sciences reviews: a quarterly publication of the American College of Sports Medicine, ISSN 0091-6331, Vol. 35, Nº. 3, 2007, págs. 119-125
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Human skin blood flow increases in response to increased body core and local skin temperature via distinct reflex and local mechanisms requiring functional nitric oxide (NO) for full expression. The mechanisms mediating cutaneous vasodilation are impaired with primary aging, resulting in attenuated vasodilation. This article highlights recent findings of how age-related vascular impairments in NO signaling contribute to attenuated cutaneous vasodilation.