Resumen de Adaptive response to ionizing radiation on Saccharomyces cerevisiae

Victor Gillette, Maria Van Broock, Diego Libkind Frati, Jorge L. Durand

• It is known that low doses of ionizing radiation called conditioning doses may induce resistance in exposed organisms to higher doses called challenging doses, and applied after a known period of time. Mechanisms involved in this phenomenon called Adaptive response are diverse and complex. The most important are the activation of DNA-repair enzymes and nuclear recombination processes. An aqueous suspension of the Baker¿s yeast Saccharomyces cerevisiae type strain was used as "target". Adaptive response was verified by measuring the population survival in a wide range of challenging doses. Inductors of radio-resistance or conditioning doses were (0.44? 0.03) Gy, and the lag time between them and the challenging doses was 2 hours at room temperature.