Two Pathways to NF-κB

• Autores: Joel L. Pomerantz, David Baltimore
• Localización: Molecular cell, ISSN 1097-2765, Nº 10, 2002, págs. 693-694
• Idioma: inglés
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• Resumen

  • NF-κB is a transcription factor that is critical for innate and adaptive immunity. Recently, a noncanonical pathway for NF-κB activation has emerged. Four recent papers provide physiological roles for this pathway and expand our understanding of lymphoid development and organogenesis with potential applications in the treatment of autoimmune disease.