The Paradoxical Relationship between NHEJ and Telomeric Fusion

• Autores: Arthur J. Lustig, Bridget Williams
• Localización: Molecular cell, ISSN 1097-2765, Vol. 11, Nº 5, 2003, pág. 1125
• Idioma: inglés
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• Resumen

  • Recent results shed new light on the origin of fusion products observed in the destabilized chromosomes of cancer and related diseases. These findings define an unusual relationship between nonhomologous end joining (NHEJ) and telomere “capping,” with identical proteins playing opposing roles.