Regulation of septin organization and function in yeast

• Mark S. Longtine ^[1] ; Erfei Bi ^[2]
  1. [1] Oklahoma State University

     Oklahoma State University

     Estados Unidos

     
  2. [2] University of Pennsylvania

     University of Pennsylvania

     City of Philadelphia, Estados Unidos

     
• Localización: Trends in cell biology, ISSN 0962-8924, Vol. 13, Nº 8, 2003, págs. 403-409
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Septins are a conserved eukaryotic family of GTP-binding filament-forming proteins with functions in cytokinesis and other processes. In the budding yeast Saccharomyces cerevisiae, septins initially localize to the presumptive bud site and then to the cortex of the mother–bud neck as an hourglass structure. During cytokinesis, the septin hourglass splits and single septin rings partition with each of the resulting cells. Septins are thought to function in diverse processes in S. cerevisiae, mainly by acting as a scaffold to direct the neck localization of septin-associated proteins.