Resumen de Changing perspectives on the perinatal management of isolated congenital diaphragmatic hernia in Europe
Jan Deprest, Eduardo Gratacós Solsona, Kypros H. Nicolaides, Elise Done, Tim van M¡eghem, Leonardo Gucciardo, Filip Claus, Anne Debeer, Karel Allegaert, Irwin Reiss, Dick Tibboel
Congenital diaphragmatic hernia (CDH) should be diagnosed in the prenatal period and prompt referral to a tertiary referral center for imaging, genetic testing, and multidisciplinary counseling. Individual prediction of prognosis is based on the absence of additional anomalies, lung size, and liver herniation. In severe cases, a prenatal endotracheal balloon procedure is currently being offered at specialized centers. Fetal intervention is now also offered to milder cases within a trial, hypothesizing that this may reduce the occurrence of bronchopulmonary dysplasia in survivors. Postnatal management has been standardized by European high-volume centers for the purpose of this and other trials.
