Circulating T-Regulatory Cells, Exercise and the Elite Adolescent Swimmer

• Autores: Lori D. Wilson, Frank Zaldivar, Christina D. Schwindt
• Localización: Pediatric exercise science, ISSN 0899-8493, Vol. 21, Nº. 3, 2009, págs. 305-317
• Idioma: inglés
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• Resumen

  • Brief high intensity exercise induces peripheral leukocytosis possibly leading to a higher incidence of allergic symptoms in athletes undergoing excessive training. We studied the exercise-induced alternation of circulating Tregs and FoxP3+ Tregs due to acute intense swim exercise in elite swimmers (n = 22, 12 males, age = 15.4 yrs). Twelve had prior or current rhinitis or asthma and 10 had no current or prior allergy or asthma. Circulating Tregs increased significantly (p < .001) following exercise (pre = 133 ± 11.2, post = 196 ± 17.6) as did FoxP3+ cells (pre = 44, post = 64 cells/?l). Increases in Tregs and FoxP3+ Tregs occurred to the same extent in both groups of adolescent swimmers.