Vitamin D and breast cancer: a short review

• Autores: Beatríz A. Mendoza, Alvaro L. Ronco
• Localización: Biomedicina, ISSN 1510-9747, ISSN-e 1688-2504, Vol. 3, Nº. 2, 2007, págs. 139-148
• Idioma: inglés
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• Resumen

  • The literature about vitamin D level and risk of breast cancer (BC) supports currently a role in cancer prevention. Recently, dairy calcium and total vitamin D intake have shown inverse associations with premenopausal BC risk, although authors had recognized before that their independent associations with BC were difficult to distinguish. Moreover, dietary vitamin D is frequently negligible: sunlight exposure and fortified foods seem to be its major sources. Besides, the available literature enables to link vitamin D tightly with some of light of the analyzed bibliography, it is reasonable to think that vitamin D is located in a crossroad of several metabolic AND hormonal pathways which are likely important for the occurrence and/or development of BC. Considering that human breast cells have vitamin D receptors, there is a biologically plausible basis for the hypothesis that vitamin D contributes to protect against BC.