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Long-Term Determinants of Muscle Strength Decline:: Prospective Evidence from the 22-Year Mini-Finland Follow-Up Survey

  • Autores: Sari S. Stenholm, Kristina Tiainen, Taina Rantanen, Päivi Sainio, Markku M. Heliövaara, Olli Impivaara, Seppo Koskinen
  • Localización: Journal of the American Geriatrics Society, ISSN 0002-8614, Vol. 60, Nº. 1, 2012, págs. 77-85
  • Idioma: inglés
  • Texto completo no disponible (Saber más ...)
  • Resumen
    • Objectives: To examine long-term changes in handgrip strength and the factors predicting handgrip strength decline.

      Design: Longitudinal cohort study with 22 years of follow-up.

      Setting: Population-based Mini-Finland Health Examination Survey in Finland.

      Participants: Nine hundred sixty-three men and women aged 30 to 73 at baseline.

      Measurements: Handgrip strength was measured using a handheld dynamometer at baseline and follow-up. Information on potential risk factors, namely lifestyle and chronic conditions, and their changes throughout the follow-up were based on health interviews.

      Results: Based on linear mixed-effect models, midlife physically strenuous work, excess body weight, smoking, cardiovascular disease, hypertension, diabetes mellitus, and asthma predicted muscle strength decline over 22 years of follow-up (P < .05 for all). In addition, pronounced weight loss, becoming physically sedentary, persistent smoking, incident coronary heart disease, other cardiovascular disease, diabetes mellitus, chronic bronchitis, chronic back syndrome, long-lasting cardiovascular disease, hypertension, and asthma were associated with accelerated handgrip strength decline (P < .05 for all).

      Conclusion: Lifestyle and physical health earlier in life determine rate of muscle strength decline in old age. Efforts should be made to recognize persons at risk in a timely manner and target early interventions to middle-aged persons to slow down muscle strength decline and prevent future functional limitations and disability.


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