Infecciones del tracto urinario: sensibilidad antimicrobiana y seguimiento clínico

• Autores: M. C. Lucas Collantes, J. Cela Alvargonzález, A.M. Angulo Chacón, M. C. García Ascaso, R. Piñeiro Pérez, María José Cilleruelo Ortega, Isabel Sánchez Romero
• Localización: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría ( AEP ), ISSN-e 1696-4608, ISSN 1695-4033, Vol. 76, Nº. 4, 2012, págs. 224-228
• Idioma: español
• Títulos paralelos:
  • Urinary tract infections: antibiotic resistance and clinical follow up
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• Resumen

  • The initial treatment of the urinary tract infections (UTI) is empirical and it is a priority to determine the antibiotic resistance of most common germs in a population. Furthermore, due to the suspicion of acute pyelonephritis the presence of renal scarring should be ruled out as this may lead to further complications.

    A retrospective longitudinal study was performed on all children under 14 years diagnosed with UTI from January 1 2009 to December 31 2009. The in vitro susceptibility to the most important urinary pathogens was analysed, along with the presence of scars, and a subsequent follow-up.

    The most frequently isolated bacteria were E. coli (80%), P. mirabilis (9.7%) and K. pneumoniae (4.2%). In the antibiogram, E coli showed a high sensitivity to fosfomycin (99.1%), cefotaxime (98.2%) cefuroxime (97.3%) and gentamicin (95.6%). The sensitivity obtained against amoxicillin-clavulanate was 83.2%, while that obtained against cotrimoxazole was 78.9%.

    Post-pyelonephritis scars were found in 19% of patients with febrile UTI, 17% out-patients and 20% of those admitted.