Regioselective Hydration of an Alkene and Analysis of the Alcohol Product by Remote Access NMR: A Classroom Demonstration

• Autores: Maureen E. Smith, Sara L. Johnson, Douglas S. Masterson
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 90, Nº 1, 2013, págs. 99-101
• Idioma: inglés
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• Resumen

  • A two-part demonstration was conducted in our first-semester organic chemistry course designed to introduce students to the formation of alcohols, regioselective reactions, and analysis of organic products by NMR analysis. This demonstration utilized the oxymercuration-demercuration sequence to prepare an alcohol from an alkene in a Markovnikov manner because the reaction is easy to execute and has a dramatic, observable color change during the transformation. The alcohol product produced was then utilized in a classroom demonstration of 1H NMR using a remote accessible NMR spectrometer.