A Critical Evaluation of Glycated Protein Parameters in Advanced Nephropathy: A Matter of Life or Death: Time to dispense with the hemoglobin A1C in end-stage kidney disease

• Autores: Barrry I Freedman
• Localización: Diabetes care, ISSN-e 0149-5992, Vol. 35, Nº. 7, 2012, págs. 1621-1624
• Idioma: inglés
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• Resumen

  • There remains a critical need to identify accurate assays for measuring recent glycémie control in patients with ESKD, in whom mortality rates are 15-20% per year, predominantly from cardiovascular disease (CVD). [...]accurate measures are identified, it will be difficult to clearly determine the effects of better blood glucose control on hospitalization and mortality rates in patients on chronic dialysis therapy. [...]care must be exercised when using glucose dehydrogenase pyrroloquinoline quinone glucometers in peritoneal dialysis patients who use icodextrin dialysate, because of interference with the assay and overestimation of serum glucose levels (28).