Resumen de Insulin Detemir in Pregnancy: A Small but Significant Step Forward
Two large randomized controlled trials (4,5) of women with gestational diabetes mellitus, variously diagnosed, have demonstrated that treating and reducing glucose levels during pregnancy reduces many of these complications. The study does provide reassurance for its use when the standard long-acting insulin preparations are not achieving appropriate glycémic control, safely. Because the study suggested that insulin detemir was able to achieve lower fasting plasma glucose concentrations without increasing the risk of the feared nocturnal hypoglycemia, it will influence the choice of long-acting insulin in women who have difficulty in safely achieving fasting glucose targets.
