Matthew R. Dintzner, Charles R. Kinzie, Kimberly Pulkrabek, Anthony F. Arena
A one-term synthesis project that incorporates many of the principles of green chemistry is presented for the undergraduate organic laboratory. In this multistep scheme of reactions, students react, recycle, and ultimately convert cyclohexanol to nylon 6,6. The individual reactions in the project employ environmentally friendly methodologies, and the scheme minimizes impact on the environment by reducing waste, using the product of one reaction as the starting material for the next.
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