Resumen de A research-based undergraduate organic laboratory project: investigation of a one-pot, multicomponent, environmentally friendly prins-friedel-crafts-type reaction
Matthew R. Dintzner, Justin J. Maresh, Charles R. Kinzie, Anthony F. Arena, Thomas Speltz
Students in the undergraduate organic laboratory synthesize tetrahydro-2-(4-nitrophenyl)-4-phenyl-2H-pyran via the Montmorillonite K10 clay-catalyzed reaction of p-nitrobenzaldehye with methanol, 3-buten-1-ol, and benzene. The synthesis comprises an environmentally friendly tandem Prins-Friedel-Crafts-type multicomponent reaction (MCR) and sets the stage for investigation of reaction scope through student research projects with other carbonyl substrates.
