Resumen de Estudio de la adsorción de insulina en las bolsas de nutrición parenteral: Influencia del tiempo de administración y la temperatura
G. Rodríguez Torné, A. A. Castelo Luque, Juan Francisco Marín Pozo, J.M. Arias de Saavedra Alías, M. J. Martín Barranco
The influence of both perfusion time and storage temperature is studied with the purpose of determining the loss of insulin due to adsorption when it is added to parenteral nutrition bags. There were added 20 IU of regular insulin to two mixtures of equal parenteral nutrition composition, preserving one of them at 4-8 °C for 24 hours prior to its perfusion while the other was perfused after its preparation. Measurement times were at zero time, 12 and 24 hours. Adsorption in both cases shows an evident increasing trend and a significant stationary character following a Langmuir adsorption isotherm. Although an even slighter recovery is observed in bags preserved at 4-8 °C, temperature does not influence in a significant manner on the adsorption process
