Planctomycetes�Verrucomicrobia�Chlamydiae (PVC) bacteria have features that differentiate them from classical Gram-negative (G�) bacteria. One such feature is their complex endomembrane system. Based on the difference of membrane organization and compartment identity, PVC bacteria were proposed to form an exception to the bacterial G� cell plan. Here I argue that all PVC membranes are derived from G� membranes, and that their organization and the compartments they form are similar to those of G� bacteria. I suggest that PVC membrane organization should be evaluated within a G� framework and as a variation of it.
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