A new itch to scratch for TSLP

• Autores: Matthew J. Turner, Baohua Zhou
• Localización: Trends in immunology, ISSN 1471-4906, Vol. 35, Nº. 2, 2014, págs. 49-50
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Atopic dermatitis (AD) is characterized by allergic inflammation and itch. Thymic stromal lymphopoietin (TSLP) is a pro-allergic cytokine implicated in AD. A paper in Cell transforms the understanding of the functional repertoire of TSLP in general and in AD in particular showing that TSLP can directly stimulate sensory neurons and provoke itch.