To compare the effectiveness of multi-stage and one-stage alternating low-pressure air mattresses (ALPAM) and alternating pressure air mattress (APAM) overlays in preventing pressure ulcers among hospitalized patients, data were pooled (N?=?617) from a study of patients allocated to multi-stage ALPAM (n?=?252) or one-stage ALPAM (n?=?264), and another study of patients allocated to APAM overlay (n?=?101). Cumulative pressure ulcer incidence was 4.9% (n?=?30) over 14 days. Fewer ulcers developed on multi-stage ALPAM compared with APAM overlay (OR?=?0.33; 95% CI [0.11, 0.97]), but no difference was found between one-stage ALPAM and APAM overlay (OR?=?0.40; 95% CI [0.14, 1.10]). Time to develop ulcers did not differ by mattress type.
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