Complications of Diabetes Therapy

• Autores: Sarah D. Corathers, Shawn Peavie, Marzieh Salehi
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 42, Nº. 4, 2013 (Ejemplar dedicado a: Acute and Chronic Complications of Diabetes), págs. 947-970
• Idioma: inglés
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• Resumen

  • Current strategies for the treatment of type 2 diabetes mellitus promote individualized plans to achieve target glucose levels on a patient-by-patient basis while minimizing treatment related risks. Maintaining glycemic control over time is a significant challenge because of the progressive nature of diabetes as a result of declining ?-cell function. This article identifies complications of non-insulin treatments for diabetes. The major classes of medications are reviewed with special focus on target population, mechanism of action, effect on weight, cardiovascular outcomes and additional class-specific side effects including effects on bone. Effects on ?-cell function are also highlighted.