Urinary Tract Infection Pathogenesis: Host Factors

• Autores: Ann E. Stapleton
• Localización: Infectious disease clinics of North America, ISSN 0891-5520, Vol. 28, Nº. 1, 2014 (Ejemplar dedicado a: Urinary tract infections: diagnostic and management issues), págs. 149-159
• Idioma: inglés
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• Resumen

  • Clinically, host factors in the pathogenesis of urinary tract infection (UTI) may be considered as modifiable (eg, behaviors associated with increased risk of UTI, anatomic and functional problems of the urinary tract) and thus potentially amenable to a change in patient behavior or treatment approach, or as intrinsic and nonmodifiable host factors that neither the patient nor the clinician can influence (eg, gender and genetic influences associated with UTI). Although considering nonmodifiable host factors may be discouraging to patients and clinicians at present, some genetic associations have the potential for future predictive value and may interface with future treatments.