Resumen de Loop de loop: viral RNA evades IFIT1 targeting

Justin A. Roby, Brian D. Clarke, Alexander A. Khromykh

• In a landmark finding published in Science, Hyde et al. have demonstrated that a hairpin RNA structure adjacent to the 5' cap of alphavirus genomic RNA confers the ability of these viruses to evade restriction by the interferon-induced host protein IFIT1.