Vitamin D and Diabetes

• Autores: Joanna Mitri, Anastassios G. Pittas
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 43, Nº. 1, 2014 (Ejemplar dedicado a: Diabetes Mellitus: Associated Conditions), págs. 205-232
• Idioma: inglés
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• Resumen

  • There has been increasing evidence that vitamin D may have a role in modifying risk of diabetes. Vitamin D has both direct and indirect effects on various mechanisms related to the pathophysiology of type 2 diabetes, including pancreatic beta cell dysfunction, impaired insulin action and systemic inflammation. This article describes the biologic plausibility behind the potential association between vitamin D and type 2 diabetes and summarizes the current evidence from human studies that suggests but does not prove a relation between vitamin D and type 2 diabetes, and briefly reports on the potential association between vitamin D and type 1 diabetes.