Resumen de Reacciones adversas a beta bloqueantes
Macarena Bonilla Porras, N. Moyano Sierra, C. Capilla Montes, Eva Delgado Silveira, Benito García Díaz
Objective: To describe the adverse reactions to beta-blockers in an area-IX hospital with 420 beds. Method: A retrospective study of patients who suffered adverse reactions to beta-blockers, between the years 1998-2002, included in a pharmacosurveillance database from the pharmacy department that collects information from 3026 patients with adverse reactions to drugs. Results: Out of the total number of patients, 51 (1.68%) had adverse reactions to beta-blockers. With respect to the implicated beta-blockers, atenolol occurred in 36 of the cases (70.6%), carvedilol in 10 (19.6%), propranolol in 4 (7.84%), bisoprolol in 1 (1.96%). Out of those adverse reactions, 32 (62.75%) caused hospital admittance and 14 (37.25%) occurred during hospital stay. Conclusion: Beta-blockers are a group of drugs that, despite not quantitatively producing a high percentage of severe reactions, qualitatively produce indeed an important level of yatrogenia
