Utilización de fármacos antisecretores

• Autores: Mª A. Berrocal Javato, Mª C. Iranzu Aperte, Manuel Gómez-Serranillos Reus, G. Rodríguez Torné, G. Marcos Ruiz
• Localización: Atención Farmacéutica, ISSN 1139-7357, Vol. 6, Nº. 5, 2004, págs. 325-332
• Idioma: español
• Títulos paralelos:
  • Use of antisecretory drugs
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• Resumen

  • Objective: To know the consumption of antisecretory drugs, the prescribed guidelines and their intravenous dosage in high digestive hemorrhage (HDH). Method: The consumption of antisecretory drugs is quantified in DDD/100 stays-day in the whole hospital and by departments. The number of stays is calculated with each active principle according to the administration route and posology. Patients with gastric and duodenal ulcer hemorrhage are obtained from the CIE-9-MC and their clinical records are reviewed. Results: Total consumption was of 74.05 DDD/100 stays-day. Parenteral omeprazole is the most consumed in Surgery (46.24) and Internal Medicine (41.35) and omeprazole oral in Cardiology (56.19), Internal Medicine (48.38) and Pneumology (48.20). Prescriptions for the oral doses were apropiate inparenteral route it exists infradosage for ranitidine and overdosage for omeprazole. Proton pump inhibitors were the selected ones in HDH, predominating 40 mg/ 8 hours. Conclusions: Consumption of antisecretory drugs is centered around the PPI. Omeprazole has supposed 87.80% of the DDD/100 stays-day vs. 9.37% of ranitidine