Regulating the diverse outcomes of interferon's interference

• Autores: Heather D. Marshall, Susan M. Kaech
• Localización: Trends in immunology, ISSN 1471-4906, Vol. 35, Nº. 8, 2014, págs. 353-354
• Idioma: inglés
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• Resumen

  • Regulatory T cells are crucial for preventing autoimmunity, but how their function is restrained to allow optimal effector T cells responses in appropriate contexts is unclear. In a recent paper in the Journal of Experimental Medicine, Campbell and colleagues demonstrate that virus-induced type I interferon acts directly on Treg cells to allow for functional antiviral T cell responses.