A Safer, Discovery-Based Nucleophilic Substitution Experiment

• Autores: Gail Horowitz
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 86, Nº. 3 (March), 2009, págs. 363-364
• Idioma: inglés
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• Resumen

  • A discovery-based nucleophilic substitution experiment is described in which students compare the reactivity of chloride and iodide ions in an SN2 reaction. This experiment improves upon the well-known "Competing Nucleophiles" experiment in that it does not involve the generation of hydrogen halide gas. The experiment also introduces students to the subject of phase-transfer catalysis.