Automated Combinatorial Chemistry in the Organic Chemistry Majors Laboratory

Christopher J. Nichols ^[1] ; Larry F. Hanne ^[1]
1. [1] California State University, Chico
  
  California State University, Chico
  
  Estados Unidos
Localización: Journal of chemical education, ISSN 0021-9584, Vol. 87, Nº 1 (January), 2010, págs. 87-90
Idioma: inglés
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Resumen
- A multidisciplinary experiment has been developed in which students each synthesize a combinatorial library of 48 hydrazones with the aid of a liquid-handling robot. Each product is then subjected to a Kirby−Bauer disk diffusion assay to assess its antibacterial activity. Students gain experience working with automation and at the chemistry−biology interface.