Yu Shyr, Hom-Lay Wang, Kenneth M. Kimble, Robert M. Eber, Stephen Soehren
Treatment of Gingival Recession Using a Collagen Membrane with or without the Use of Demineralized Freeze-Dried Bone Allograft for Space Maintenance Kenneth M. Kimble Private practice, Phoenix, AZ.
Yu Shyr Division of Biostatistics, Department of Preventive Medicine, School of Medicine, Vanderbilt University, Nashville, TN.
Dr. Hom-Lay Wang Department of Periodontics/Prevention/Geriatrics, School of Dentistry, University of Michigan, Ann Arbor, MI.
Background: Studies utilizing collagen membranes for guided tissue regeneration (GTR)-based root coverage procedures have reported promising results. However, creating and maintaining space underneath the membrane remains a challenge. Therefore, the purpose of this clinical trial was to determine whether the addition of bone graft (i.e., demineralized freeze-dried bone allograft [DFDBA]) significantly affects the outcome of collagen membrane GTR-based root coverage procedures.
Results: Guided tissue regeneration with collagen (COLL) and collagen + DFDBA (COBA) both resulted in statistically signifi- cant (P <0.05) reductions in recession depth (2.1 ± 0.9 mm and 2.5 ± 0.5 mm), recession width (1.5 ± 1.7 mm and 2.2 ± 1.6 mm), increase in keratinized tissue (0.7 ± 0.8 mm and 1.2 ± 1.0 mm), and gain of clinical attachment level (2.1 ± 1.0 mm and 3.0 ± 1.0 mm), when comparing 6-month data to baseline. Mean root coverage was 68.4 ± 15.2% with COLL and 74.3 ± 11.7% with COBA. However, there were no statistically significant differences between groups for recession depth, recession width, width of keratinized tissue, clinical attachment level, and probing depth.
KEYWORDS: Bone, demineralized, bone, freeze-dried, collagen/therapeutic use, dental esthetics, gingival recession/surgery, gingival recession/therapy, grafts, bone, guided tissue regeneration, membranes, barrier
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