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Clinical Outcome Observed in Subjects with Recurrent Periodontal Disease Following Local Treatment with 25% Metronidazole Gel

  • Autores: Dr. H. Jansson, G. Bratthall, G. Söderholm
  • Localización: Journal of periodontology, ISSN 0022-3492, Vol. 74, Nº. 3, 2003, págs. 372-377
  • Idioma: inglés
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  • Resumen
    • Background: The aim of this study was to evaluate the clinical outcome in patients with recurrent periodontal disease following treatment with 25% metronidazole gel.

      Methods: Twenty subjects in a maintenance care program but with recurrent periodontal disease participated. Three months after scaling and root planing, a total of 40 sites, 2 in each patient, with probing depth ≥5 mm were selected. One site randomly selected was treated with metronidazole gel (test) and the other site with a placebo gel (control). Baseline and follow-up measurements included plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), and clinical attachment level (CAL).

      Results: There were no statistically significant differences in PI, GI, BOP, PD, or CAL between test and control sites.

      Conclusion: This study showed that local treatment with 25% metronidazole gel did not seem to influence the clinical healing in this group of subjects with recurrent periodontal disease. J Periodontol 2003;74:372-377.


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