Enamel Matrix Proteins in the Treatment of Deep Intrabony Defects
- Autores: Giuseppe Cardaropoli, Åsa S. Leonhardt
- Localización: Journal of periodontology, ISSN 0022-3492, Vol. 73, Nº. 5, 2002, págs. 501-504
- Idioma: inglés
- Enlaces
-
Resumen
Background: The present study evaluated the healing of enamel matrix derivative (EMD) proteins in the treatment of periodontal lesions with deep intrabony defects.
Methods: Ten deep intrabony defects in 7 periodontal patients were treated and followed for 1 year. The sites had a probing depth (PD) ≥8 mm; clinical attachment level (CAL) ≥9 mm, and intrabony component depth ≥5 mm. All subjects received therapy prior to surgery and had a plaque score (PI) ≤10%. Full thickness flaps were elevated buccally and lingually, granulation tissue was removed from the defects, and the root surfaces were planed. A 24% EDTA gel was applied followed by the enamel matrix protein preparation. The flaps were closed with interrupted sutures. The patients rinsed with a chlorhexidine solution twice a day for 6 weeks. They were recalled every 2 weeks for 6 months for professional tooth cleaning and then every 4 weeks for an additional 6 months. The experimental sites were reexamined 6 and 12 months after regenerative surgery.
Results: At the 1-year examination, the mean CAL gain was 6.5 mm, the mean PD was 3.2 mm, and mean radiographic bone fill was 4.7 mm.
Conclusions: The application of enamel matrix proteins in combination with open flap curettage and root planing resulted in a gain of CAL and bone fill in deep intrabony defects. J Periodontol 2002;73:501-504.
