Resumen de An Introduction to Enzyme Kinetics, Part Deux
Rate equations for enzyme-catalyzed reactions are derived and presented in a way that makes it easier for the nonspecialist to see how the rate of an enzyme-catalyzed reaction depends upon macroscopic kinetic constants and concentrations. Distribution equations are used to show how the rate of the reaction depends upon the relative quantities of the various enzyme species in the reaction mixture. This approach is introduced and reviewed as it applies to single-substrate reactions without inhibition, with competitive inhibition, with uncompetitive inhibition, and with noncompetitive inhibition. Then, this approach is extended to the ordered two-substrate reaction, the two-substrate random rapid equilibrium reaction, and the two-substrate ping-pong reaction.
