Resumen de Selected Highlights from other Journals: Screening diabetic cats for hypersomatotropism
S.J.M. Niessen, Y. Forcada, P. Mantis, R. Fowkes, N. Harrington
NATURALLY occurring diabetes mellitus (DM) is currently estimated to affect approximately 1 in 200 household cats in the UK, and the number is thought to be rising. Feline DM is therefore an important veterinary endocrinopathy, but has also been increasingly studied as a model for human type 2 DM as it shares many characteristics with human DM. Although feline type 2 DM is the most common type of spontaneous DM in cats, other types have been described, particularly DM caused by endogenous overproduction of hormones with an insulin-antagonistic effect, such as cortisol (hyperadrenocorticism) or growth hormone (hypersomatotropism [HS]). This study estimated the prevalence of HS in a large cohort of diabetic cats.
A total of 1221 diabetic cats were screened for HS and were classified as suspected of having HS-induced DM on the basis of elevation of serum total insulin-like growth factor-1 (IGF-1) concentration of above 1000 ng/ml. Owners of cats that had a serum IGF-1 concentration above 1000 ng/ml were then invited to have a pituitary computed tomography (CT) performed on their cat. If the CT proved unremarkable, pituitary magnetic resonance imaging (MRI) was performed....
