Resumen de Obesity as a risk factor in cancer: A national consensus of the Spanish Society for the Study of Obesity and the Spanish Society of Medical Oncology
Alberto Goday Arno, Isidoro C. Barneto, José Manuel García Almeida, Ana Blasco Cordellat, Albert Lecube Torelló, Cristina Grávalos Castro, Purificación Martínez de Icaya Ortiz de Urbina, Ramón de las Peñas Bataller, Susana Monereo Megías, Lidia Vázquez Tuñas, J.E. Palacio Abizanda, Pedro Pérez Segura
In the last few years, many prospective studies have demonstrated a clear association between obesity and cancers of the colon and rectum, breast in post-menopausal women, endometrium, kidney, oesophagus and pancreas. Obesity is also associated with a high risk of recurrence and cancer-related death. The pathophysiology of obesity involves various changes that may be implicated in the relationship between obesity and cancer, such as excess inflammatory cytokines and chronic inflammation, hyperinsulinaemia, insulin resistance, and raised leptin and oestrogens. The Spanish Society for the Study of Obesity and the Spanish Society of Medical Oncology have signed a cooperation agreement to work together towards reducing the impact of obesity in cancer. Preventing obesity prevents cancer.
