Hypopituitarism After Traumatic Brain Injury

• Autores: Eva Fernández Rodríguez, Ignacio Bernabeu Morón, Ana I. Castro, Felipe Casanueva Freijó
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 44, Nº. 1, 2015, págs. 151-159
• Idioma: inglés
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• Resumen

  • The prevalence of hypopituitarism after traumatic brain (TBI) injury is widely variable in the literature; a meta-analysis determined a pooled prevalence of anterior hypopituitarism of 27.5%. Growth hormone deficiency is the most prevalent hormone insufficiency after TBI; however, the prevalence of each type of pituitary deficiency is influenced by the assays used for diagnosis, severity of head trauma, and time of evaluation. Recent studies have demonstrated improvement in cognitive function and cognitive quality of life with substitution therapy in GH-deficient patients after TBI.