Detecting virulence and drug-resistance mycobacterial phenotypes in vivo

• Autores: Graham S. Timmins
• Localización: Trends in microbiology, ISSN 0966-842X, Vol. 23, Nº. 6, 2015, págs. 321-323
• Idioma: inglés
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• Resumen

  • Bacterial phenotypes are predominantly studied in culture because detection of their specific metabolic pathways in the host is challenging. Development of stable-isotope breath tests, allowing in situ phenotype analyses, may endow diagnostics with new modalities based upon direct monitoring of in vivo microbial metabolism and host–pathogen phenotypic interactions.