Infectious asthma triggers: time to revise the hygiene hypothesis?

• Autores: Wilmore C. Webley, Kelly L. Aldridge
• Localización: Trends in microbiology, ISSN 0966-842X, Vol. 23, Nº. 7, 2015, págs. 389-391
• Idioma: inglés
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• Resumen

  • The hygiene hypothesis supports an inverse relationship between respiratory infections in early-life and atopic diseases. However, a recent study supports growing evidence that early-life infection and airway microbiome composition can significantly influence asthma inception and exacerbation later in life. This reignites discussions on infection-mediated asthma phenotypes and potential therapeutics.