Sophie Brameyer, Helge B. Bode, Ralf Heermann
Gram-negative bacteria use N-acyl homoserine lactones (acyl-HSLs) for communication, predominantly mediated by LuxR-type receptors. Recent studies uncovered aryl-HSLs, α-pyrones and dialkylresorcinols as further chemical languages of Gram-negative bacteria. These findings extend the number of bacterial signaling molecules and suggest that cell–cell communication goes far beyond acyl-HSL signaling in nature.
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